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Development of a novel humanized gut-brain axis model as a tool toward personalized nutrition

AbstractIntestinal luminal microbial metabolites affect tryptophan and serotonin metabolism, and cross or modify the blood-brain barrier (BBB). Understanding those mechanisms further necessitates integrated gut-brain axis model systems. Using an ex vivo-in vitro approach, H2O2-stressed or… Development of a novel humanized gut-brain axis model as a tool toward personalized nutrition

NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction

AbstractMissing and inconsistent nutrient values in food-composition databases hinder comparative nutrition research. We present NutriMatch, a scalable harmonization method that embeds food descriptions with a large-language model, aligns nutritionally equivalent items, and imputes missing nutrients… NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction