Provisionally accepted1Tongji University Affiliated Shanghai Pulmonary Hospital, Shanghai, China2Laboratory of Microbiology, Immunology, and Metabolism, DiPROBIO (Shanghai) Co., Ltd., Shanghai, China, Shanghai, China3Tsinghua University Vanke School of Public Health, Beijing, ChinaBackground: International travel exposes individuals to…
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AbstractIntestinal luminal microbial metabolites affect tryptophan and serotonin metabolism, and cross or modify the blood-brain barrier (BBB). Understanding those mechanisms further necessitates integrated gut-brain axis model systems. Using an ex vivo-in vitro approach, H2O2-stressed or…